A total 1,118 jobs have been created across the Waterside Enterprise Zone, 23 per cent above the original government target of 908.
It has also brought £152 million of provate sector investment into the town.
The figures formed part of a presentation by leaders of the South East Midlands Local Enterprise Partnership of the outcomes of its 2015 Action Plan to the Department of Communities and Local Government.
SEMLEP chair Dr Ann Limb said: “The impact of SEMLEP’s Enterprise Zone on the economy in Northampton is clear for all to see, with companies from high growth industries keen to move to the town and do business here.
“The benefits will be long-lasting, with thousands of jobs being created for local people.
“Northampton is a town on the up and as investment into the Enterprise Zone continues to pour in, it will provide the catalyst for further growth."
The Waterside Enterprise Zone comprises more than 20 sites along the River Nene, stretching from Sixfields in the west across the town centre, and incorporates brownfield development opportunities, growing industrial estates and expanding sports stadium sites.
Companies to have reaped the rewards of the economic advantages available to businesses in the Enterprise Zone include engineering firm Cosworth, which has taken on 70 highly skilled engineering workers and 15 apprentices, and Carlsberg, which has created 67 new jobs and secured £25 million of private sector investment.
Northampton South MP David Mackintosh, the former leader of Northampton Borough Council, said: “The Enterprise Zone has been a big catalyst for growth in Northampton to help with the regeneration of the town.
"I am pleased to see how well the Enterprise Zone has developed and I will continue to fight in Parliament for further investment from government in the infrastructure in Northampton and to use my position to promote Northampton and the opportunities the Enterprise Zone provides to encourage more investment in the town.”
SEMLEP’s investment in the Enterprise Zone has included £5 million towards the new railway station, £3 million to improve the road infrastructure in the area and £3.6 million towards improvements to St James Mill Road.
It has also played a pivotal role in securing borrowing of £46 million for the new University of Northampton campus.